Kugadzira Maitiro Ekuronga Nzira Kubva pane Chaicho Kusatapukira

Zvinoenderana nekuongororwa kwechimiro chekutsvagisa, mukushandiswa kweiyo yakangwara algorithm munzira yekuronga nzira ye spacecraft shell zvikamu, iyo algorithm mhedzisiro haina kunaka nekuda kwehuwandu hwekugadzirisa maficha. Mune hungwaru algorithms, AIS inotsamira pane yayo cloning meshini kuti iwane yakakura mabhenefiti mukumhanya kweiyo algorithm, asi ine dhizaini yekuwira nyore nyore mumhinduro yemunharaunda, iyo inodzikamisa zvakanyanya kuita kwegorgorithm.

Panyaya iyi, chitsauko chino chinovandudza artificial immune algorithm nekuongorora iyo chaiyo immune process, uye inokurudzira nzira yehungwaru yekuronga nzira inoenderana neyakagadzirwa chaiyo immune algorithm (Artificial Specific Immune System, ASIS). Iyo ASIS algorithm inotevedzera kubayiwa uye inoshandisa iyo Dijkstra algorithm kugadzira emhando yepamusoro masoja ekutanga ekudzivirira. Pahwaro uhwu, antibody inoumbwa uye inoshandurwa kuburikidza neyakagadzirwa immune algorithm kuti iwane yakanyanya antibody.

Specific Immunity Concept Mepu yeMaitiro eKuronga Nzira

Iyo biological immune system yakagoverwa uye yakazvimiririra ruzivo rwekugadzirisa hurongwa, inoratidza parallelism, kugovera, kuzvigadzirisa, kuzvironga uye humwe hunhu, nekuzivikanwa kwakasimba, kudzidza uye ndangariro kugona. Kana antigen inoonekwa nehutachiona, masero e-antigen-presenting akadai se macrophages anodya uye anochera antigen, uye anoratidza antigenic determinants pamusoro pepamusoro, iyo inozivikanwa nemasero ekudzivirira muviri akadai seB masero uye T masero. 

Mushure mekuziva iyo antigen, masero ekudzivirira anovhara uye mutate (anonzi kupararira uye kusiyanisa mu immunology), anobudisa zvirwere zvakasiyana-siyana, anosunga kune antigen kubvisa antigen. Pakati pavo, cloning uye kuchinja kwemaitiro emasero ekudzivirira muviri kunotungamirirwa nehutano hwekudzivirira zvirwere, kusanganisira nzira mbiri dzekugadzirisa, hutungamiri hwakanaka uye hutsika husina kunaka.

Nekudaro, muhupenyu chaihwo, nekuda kwehuviri hwakasimba hwezvimwe zvirwere zvitsva, immune system haigone kuzvibvisa munguva pfupi. Naizvozvo, jekiseni rekugadzira rinowanzoshandiswa kutungamira kugadzirwa kweantibody uye nekumhanyisa maitiro ekudzivirira. Pakati pavo, kushandiswa kwejekiseni rekugadzira kugadzira masoja ekudzivirira chirwere kunonzi chaiyo immunity.

Saizvozvo, mukugadzira nzira yekuronga, huwandu hwekugadzirisa maficha e spacecraft shell zvikamu zvakakura, izvo zvinoita kuti artificial immune algorithm iwire nyore mune yemuno optimum, uye yekupedzisira mhedzisiro haizadzise zvinodiwa neinjiniya. Naizvozvo, chinyorwa ichi chinokwevera pane chaiyo immune system, inomisa iyo ASIS algorithm modhi, uye inoita maitiro ekuronga nzira. Zvinoenderana netsanangudzo muchikamu 2.2, iyo mepu yepfungwa yekuronga nzira yekuronga muASIS algorithm inopihwa:

• (1) Antigen inoreva nhanho yekushanda matrix, uye antigenic determinants inoreva maparamita ari munhanho yekushanda matrix.
• (2) Antibody inoreva nzira inogadzirwa neASIS.
• (3) Vaccine inoreva Dijkstra algorithm. Iyo yemhando yepamusoro antibody inogadzirwa neiyo vaccine chiito inoreva nzira yemhando yepamusoro yekutanga inogadzirwa neDijkstra algorithm.
• (4) Kuvhara uye kushanduka kunoreva kuti nzira yekushanda inowedzerwa muhuwandu kuburikidza nekudzokorora, uye matanho ekugadzirisa uye kutevedzana kwemaitiro ekugadzirisa nzira inotsinhaniswa kuburikidza nekugadzirisa nzira.
• (5) Positive regulation uye negative regulation Positive regulation inoreva nzira yekugadzirisa inobva pakubatana. 

Affinity inoratidza kunaka kwenzira yemaitiro. Iyo yakakwirira yemhando yenzira yemaitiro, iyo yakakwirira hukama; kugadzirisa kwakashata kunoreva nzira yekugadzirisa inobva pakudzivisa. , Chiyero chekudzivisa chakanyatsoenderana nekugadzirisa, uye kusungirirwa kunomiririra chikamu chenzira imwechete yenzira mune yose. Iyo yakakura chikamu, iyo yakakwirira yekuisa pfungwa. Affinity uye inhibition pamwe chete zvinotarisa huwandu hwemakopi enzira yemaitiro.

Batanidza kuchinyorwa ichi: Kugadzira Maitiro Ekuronga Nzira Kubva pane Chaicho Kusatapukira

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